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Pratik Sen

Pratik Sen

PhD (IACS Jadavpur)

Professor, Department of Chemistry

Research Interest

Ultrafast Laser Spectroscopy, Even Order Nonlinear Spectroscopy, Single Molecule Spectroscopy, Biological Macromolecules (Protein, Lipid, DNA, etc.), Nanoparticles and Interfaces, Confined Environment.

Core Lab 101B, Department of Chemistry IIT Kanpur, Kanpur 208016

Specialization

Fluorescence and Ultrafast Spectroscop

Education

PhD (2006), IACS Jadavpur

M. Sc. (2001)Visva-Bharathi University

Selected Publications

Mechanistic investigation of domain specific unfolding of human serum albumin and the effect of sucrose,Protein Sci., 22, 1571 (2013).
Spectroscopic evidence of the presence of an activation barrier in the otherwise barrierless excited state potential energy surface ofauramine-O: A femtosecond fluorescence up-conversion study,J. Chem. Phys., 139, 124302 (2013).
Dielectric Controlled Excited State Relaxation Pathways of a Representative Push-Pull Stilbene: A Mechanistic Study using Femtosecond Fluorescence Up-conversion Technique,J. Chem. Phys., 138, 084308 (2013).
Quantitative estimate of the water surface pH using heterodyne-detected electronic sum frequency generation,J. Chem. Phys., 137, 151101 (2012).
Origin of Strong Synergism in Weakly Perturbed Binary Solvent System: A Case Study of Primary Alcohols and Chlorinated Methanes,J. Phys. Chem. B, 116, 1345 (2012).
Femtosecond Excited State Dynamics of 4-Nitrophenyl Pyrrolidinemethanol: Evidence of Twisted Intramolecular Charge Transfer and Intersystem Crossing involving Nitro Group,J. Phys. Chem. A, 115, 8335 (2011).

Awards & Fellowships

P. K. Kelkar Research Fellowship, Young Faculty Research fellowships, IITK, 2015
Young Scientist Medal, Indian National Science Academy, New Delhi, 2013

Professional Experience

JSPS Fellow, 2006-2008.

Indian Institute of Technology Kanpur, 2008-

Post Doc., RIKEN, Japan, 2006-2008

Current Research

The central approach of this laboratory is the mechanistic investigation of photo-induced processes of important organic and inorganic molecules in real time. Primarily we are devoted to investigate the excited state characteristics of broad range of molecules in the time scale ranging from femtoseconds to nanoseconds. The brief fields of interest include the dynamics of biological macromolecules like proteins, DNA, etc., the excited state ultrafast dynamics of many novel chromophores like fluorescent protein chromophore analogs, metal complexes, etc. Effect of nano-confinement and heterogenous media also share one of the prime locus of research in the laboratory. The main aim is to interpret natural observation and to gain complete knowledge of system property from the knowledge of excited state relaxation dynamics. In addition we are as well commencing the non-linear laser spectroscopic study of liquid-air and solid-air interfaces.
Our laboratory is equipped with

1. Femtosecond transient absorption spectrometer
2. Femtosecond fluorescence up-conversion spectrometer
3. Picosecond TCSPC system
4. Steady state fluorimeter
5. Spectrophotometer
6. Home built fluorescence correlation spectrometer etc.

Our group have studied the ultrafast excited state relaxation dynamics of important NLO dye to trace the relaxation pathways and connected to its properties. This work became one of the most read articles in The Journal of Physical Chemistry A. We also have confirmed the role of protein scaffold in reducing the non-radiative pathways, leading to highly luminescent nature of wild type GFP by studying GFP chromophore analogs. Using ultrafast laser spectroscopy, we also have measured the microviscosity of water trapped in AOT reverse-micelle to explore the possibility of using ultrafast dynamics to understand the system property.

Additional information

Prof. Pratik Sen is a Professor at the Department of Chemistry and holds the Poonam and Prabhu Goel Chair Professorship. 
 

He received his BSc and MSc degrees from the Department of Chemistry, Visva-Bharati University, in 1999 and 2001, respectively. He earned his Ph.D. from the Indian Association for the Cultivation of Science, Jadavpur, Kolkata, India, in May 2006. He joined IIT Kanpur as a faculty in December 2008. 
 

Prof. Sen’s primary research interest is to gain physical insight into how and why dynamics in various length and timescale control chemistry. His group studies systems ranging from small molecules (Ultrafast-Spectroscopy) to complex biosystems (Biophysical-Chemistry) and simple solutions (Solution-Chemistry). His group mainly uses ultrafast laser and single molecular level spectroscopies as a tool for this endeavour. Further, he intends to develop new methodologies in fluorescence spectroscopy. 
 

Prof. Sen has received several awards and recognition for his research including, Young Scientist Medal from Indian National Science Academy (INSA), Young Faculty Research Fellowship from IIT Kanpur, Member, Indian National Young Academy of Sciences (INYAS), 2016-2020; Young Faculty Research Fellowship, Ministry of Electronics & Information Technology, Government of India, Fellowship of the Royal Society of Chemistry and Bronze Medal of Chemical Research Society of India (CRSI). 
 

For more information please visit: https://home.iitk.ac.in/~psen/about.php.